By A.D. Johnson (Eds.)
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Levels of hCG are maximal during the time when testosterone synthesis begins at 8 weeks. This is prior to the earliest detection of immunoreactive FSH and LH in the pituitary gland and serum (Kaplan and Grumbach, 1976) and the initial appear ance of pituitary gonadotrophs (Baker and Jaffe, 1975) at 10 to \θ\ weeks. Significant amounts of pituitary gonadotropins are present in the fetal circula tion at the time that testosterone synthesis reaches peak levels (Reyes et al, 1974). The decline in testosterone production in the second half of gestation appears to be associated with a corresponding regression of pituitary gonado trophs (Pasteels et al, 1974).
Pp. 3 3 3 - 3 5 2 . Plenum, N e w York. , and Smith, K. D. ( 1 9 7 3 ) . The role of androgens in the initiation of spermatogenesis in man. / . Clin. Endocrinol. Metab. 3 7 , 7 4 6 . Stinnakre, M. G. ( 1 9 7 5 ) . Arch. Anat. Microsc. Morphol. Exp. 6 4 , 4 5 . Swanson, Η. H. ( 1 9 7 0 ) . Effects of castration at birth in hamsters of b o t h sexes on luteinization of ovarian implants, oestrous cycles and sexual behaviour. / . Reprod. Fertil. 2 1 , 1 8 3 . Swerdloff, R. , Walsh, P. C , Jacobs, H.
Compara tive studies on steroid sulfokinase in the human fetal testis and adrenal J. Clin. Endocrinol. Metab. 3 3 , 5 9 2 . Jirasek, J. E. ( 1 9 7 1 ) . " Johns Hopkins Press, Baltimore, Maryland. Josso, N. ( 1 9 7 1 ) . Interspecific character of the Miillerian-inhibiting substance: Action of the human fetal testis, ovary and adrenal on the fetal rat Miillerian duct in organ culture. J. Clin. Endocrinol. Metab. 3 2 , 4 0 4 . Josso, N. ( 1 9 7 2 ) . Permeability of membranes to the Miillerian-inhibiting substance syn thesized by the human fetal testis in vitro'.
Advances in Physiology, Biochemistry, and Function by A.D. Johnson (Eds.)