Atlas of Human Tumor Cell Lines by Robert K.M. Hay, Jae-Gahb Park, Adi Gazdar PDF

By Robert K.M. Hay, Jae-Gahb Park, Adi Gazdar

ISBN-10: 0123335302

ISBN-13: 9780123335302

Human tumor cells in tradition are precious for learning melanoma motives and homes. this useful reference presents valuable details for melanoma researchers on favourite, confirmed tumor mobilephone strains of the most important human organ systems.
Atlas of Human Tumor mobile Lines comprises information approximately morphological, metabolic, genetic, and progress features of human tumor cells, with morphological features provided in additional than 250 photomicrographs. It additionally includes details for developing and keeping human tumor telephone traces in tradition, and every bankruptcy covers destiny views.

* Covers well-characterized tumor mobilephone strains from the foremost human organ systems
* offers over 250 photomicrographs, either phase-contrast and electron micrographs
* incorporates a record of key references for every chapter
* Written by means of world-renowned experts

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Harsh, G. , Keating, M. , Escobedo, J. , and Williams, L. T. (1990). Platelet derived growth factor (PDGF) autocrine components in human tumor cell lines. J. Neurooncol. 8, 1-12. Hart, I. , Richardson, W. , and Raff, M. (1989). PDGF receptors on cells of the oligodendrocyte-type-2 astrocyte (0-2A) cell lineage. Development 105, 595603. , Wikstrand, C. , Friedman, H. , Bigner, S. , Trojanowski, J. , and Bigner, D. D. (1991). Differentiation characteristics of newly established medulloblastoma cell lines (D384 Med, D425 Med, and D458 Med) and their transplantable xenografts.

Neurol. 51, 272-280. , and Van Obberghen, E. (1988). Expression of two types of receptor for insulin-like growth factors in human malignant glioma. Cancer Res. 48, 1233-1237. Geller, H. , and Dubois-Dalcq, M. (1988). Antigenic and functional characterization of a rat central nervous system-derived cell line immortalized by a retroviral vector. J. Cell Biol. 107, 1977-1986. Gerosa, M. , De Carli, L, and Delia Valle, G. (1989). Overexpression of N-ras oncogene and epidermal growth factor receptor gene in human glioblastomas.

The rearranged gene encodes a truncated mRNA that lacks the coding sequence for a functioning Abl protein, lacking the tyrosine kinase domain. The significanceof thisfinding is unknown. Studiesof fourgliomacell lines (HeRo, A-172, T-406, T-508) showed a moderate amplification of c-myb in two cases (HeRo and T-406) but no relative increase in the corresponding mRNA level (Welter et 2 Human Glioma Cell Lines 29 ai, 1990). , 1989). All cell lines but one were shown to express c-myc mRNA, whereas none expressed N-myc mRNA.

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Atlas of Human Tumor Cell Lines by Robert K.M. Hay, Jae-Gahb Park, Adi Gazdar

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